| |
|
|

DISCLAIMER
| JOB OPPORTUNITIES
| OFFICE &
INSURANCE | BACK TO TOP
| CONTACT US
|
BACK TO TOP |
An
Intro For The Physician
Dear Colleague,
Electron Beam Tomography (EBT), formerly known
as Ultrafast CT, has emerged as the most powerful screening tool for subclinical
atherosclerosis in the asymptomatic or equivocally symptomatic individual.
This noninvasive x-ray examination, accomplished in an easily performed
30-second breath-hold, identifies and quantitates the amount of calcified
plaque in the coronary arteries in an accurate and reproducible fashion.
The amount of calcified plaque is closely related to the total plaque
burden and to the likelihood of obstructive coronary disease.
While the detection of obstructive disease is important, it is well established
that 68% of myocardial infarctions occur in the setting of vessels
that are <50% narrowed and are therefore NOT detectable by any form
of stress testing. Consequently, for 150,000 Americans who present
annually with sudden death, the first symptom is the last symptom. At
least 95% of these patients can be identified by EBT and afforded the
opportunity for aggressive risk factor modification to avoid their fate.
There is NO false positive EBT examination. Calcified plaque is ALWAYS
associated with atherosclerosis; the specificity is 100% and less than
5% of coronary events occur in the absence of calcified plaque.
EBT is exponentially the most powerful predictor of cardiac prognosis;
asymptomatic patients with high calcium scores have a 10 to 40 times greater
likelihood of a cardiac event over 2 to 4 years. It is 8 times more powerful
than all conventional risk factors in predicting outcome. EBT identifies
the vulnerable patient. Dr. Scott Grundy, the chairman of the National
Cholesterol Education Program Guidelines Committee, has recommended that
the calcium percentile, which compares the amount of calcium to people
of the same age and gender, become an integral part of risk assessment.
Other important uses of EBT are to determine which patents require stress
testing, based upon the amount of calcified plaque, and to track the effects
of treatment on the progression of disease by repeating the exam after
an interval of one year.
The Society of Atherosclerosis Imaging has recommended that men age 35
to 65 and women age 45 to 75 undergo EBT, particularly if there are any
risk factors. Older patients may also benefit, depending on their clinical
situation. These guidelines are applicable only for EBT. Other CT technologies
offer calcium scores but have not been validated, and expose the patient
to 4-10 times more radiation than EBT.
EBT is now available at the Heart & Vascular Institute in Morristown.
The toll free number is 866.777.SCAN (7226). The cost of the scan is $450
and is not yet covered by most insurance companies. A recent fasting lipid
profile should accompany the patient or may be drawn at the time of the
exam, if so desired. The EBT will be analyzed immediately and the results
discussed with the patient. The report and recommendations will be sent
promptly to the primary physician. We welcome the opportunity to personally
communicate with you as well.
A sample report, graphic review of the most recent EBT prognostic studies
and a reprint of a just published study comparing EBT and traditional
NCEP risk factors are enclosed.
The physicians at the Heart & Vascular Institute are delighted to
introduce this new technology that promises to be the cornerstone of prevention.
For the first time, you and your patients have the opportunity to identify
coronary disease in its earliest stages and to then modify the course
of the most prevalent disease in America.
Sincerely,

Harvey S. Hecht, M.D., F.A.C.C.
Director, Preventive Cardiology and Electron Beam Tomography
President, Society of Atherosclerosis Imaging
|
BACK TO TOP |
An
Overview of EBT Clinical Studies
EBT
and Cardiovascular Events
Prospective
Annualized Event
Rate in 632 asymptomatic patients
over 32 months

Conclusion: Patients with coronary calcium, depending on their
score, have
an annual event rate 19-44x higher than patients without calcium.
Raggi, et al. Circulation 2000; 101:850-5.
Cardiovascular
Events in Asymptomatic Patients
EBT vs. NCEP Risk Factors

Conclusion:
Patients in the highest quartile of calcium percentile have an
annualized event rate 22x higher than patients in the lowest quartile
and 3x higher than the highest quartile of all NCEP risk factors.
Raggi, et al. Circulation 2000; 101:850-5.
Cardiovascular
Events in Asymptomatic Patients:
Contribution of EBT Calcium Score Independent
of Other Risk Factors

Conclusion: After adjustment for age, gender, hypertension, high
cholesterol,
past/current smoking and diabetes, patients with coronary calcium
were from
2.5-8x more likely to have a cardiac event, depending on the score.
Wong, et al. Amer J Cardiol 2000;86:495-8
Prediction
of Coronary Events with EBT
1172
asymptomatic patients, age 53+11 years, 3.6 years follow-up

Conclusion: Patients with coronary calcium were 14.3-20.2x more
likely to
have an event, depending on the score (3-7x higher than NCEP risk
factors)
Arad, et al. JACC 2000; 36:1253-60
|
Lung Scan

|